Dual GIP/GLP-1 Receptor Agonist · Tirzepatide · S4 Prescription Only

Mounjaro in Australia: What You Need to Know

A comprehensive guide to Mounjaro (tirzepatide) — how it works pharmacologically, TGA approval status, clinical studies, and how to access it in Australia.

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What is Mounjaro?

Mounjaro is a prescription medication containing tirzepatide, manufactured by Eli Lilly. It belongs to a class known as dual GIP/GLP-1 receptor agonists — activating two different hormone receptors rather than one. Mounjaro is registered on the Australian Register of Therapeutic Goods (ARTG) and is a Schedule 4 (S4) prescription-only medicine.

Mounjaro at a glance

Active ingredient: Tirzepatide

Drug class: Dual GIP/GLP-1 receptor agonist

Schedule: S4 — Prescription Only

Administration: Once-weekly subcutaneous injection (pre-filled pen)

ARTG registration: Yes

Manufacturer: Eli Lilly

How Does Mounjaro Work?

Mounjaro (tirzepatide) activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors simultaneously. This dual mechanism of action distinguishes it from single-agent GLP-1 receptor agonists such as semaglutide.

GLP-1 receptors are involved in glucose-dependent insulin secretion, glucagon suppression, gastric emptying, and appetite signalling. GIP receptors are also involved in glucose-dependent insulin secretion and may influence adipose tissue metabolism. By activating both, tirzepatide has a broader receptor mechanism than single GLP-1 agonists.

Mounjaro is administered as a once-weekly subcutaneous injection. Dosing starts at 2.5mg weekly and is titrated upward at four-week intervals under clinical supervision.

Clinical Studies

Tirzepatide has been evaluated in the SURMOUNT and SURPASS clinical trial programmes. Key publications include:

Clinical context: Trial outcomes represent averages from controlled study populations. Individual responses vary significantly based on health status, adherence, and other factors. Your prescriber will discuss expectations relevant to your individual circumstances.

Mounjaro in Australia — Availability & Prescription

Mounjaro requires a valid prescription from a registered Australian medical practitioner. A clinical assessment is required before any prescription can be issued — your clinician will evaluate your full medical history, current medications, and individual health circumstances.

Mounjaro is available through registered Australian pharmacies. Chemist2U's partner pharmacy network can dispense and deliver Mounjaro where it is in supply.

Speaking With Your Clinician

Whether Mounjaro is appropriate for your circumstances is a clinical decision made in consultation with a registered Australian medical practitioner. Your clinician will review your complete medical history, current medications, and individual circumstances before making any prescribing decision.

An informed consultation is the most important step. Be thorough and open with your clinician — they can only make a safe clinical decision with complete information about your health history and current circumstances.

Important: Do not start, stop, or modify any prescription medication without consulting your clinician first. An ongoing care plan with clinical oversight is a key part of responsible use of any prescription medication.

What to Expect

Mounjaro is administered once weekly via subcutaneous injection. Dosing begins at 2.5mg and is gradually increased under clinical guidance. Common side effects from clinical trials include nausea, diarrhoea, vomiting, and constipation — typically most notable during dose escalation.

The TGA-approved Consumer Medicine Information (CMI) for Mounjaro provides a complete side effect profile and is available from your dispensing pharmacist.

See also: Ozempic and Mounjaro: Understanding the Difference

Frequently Asked Questions

Is Mounjaro available in Australia?

Yes. Mounjaro (tirzepatide) is registered on the Australian Register of Therapeutic Goods (ARTG) and available through registered pharmacies with a valid prescription from a registered Australian medical practitioner. It is a Schedule 4 (S4) prescription-only medicine.

How much does Mounjaro cost in Australia?

Mounjaro is currently accessed privately in Australia for most purposes. Costs vary by dose and supplier. Your prescriber or pharmacist can provide current pricing information.

Is Mounjaro available at Chemist Warehouse?

Mounjaro can be dispensed at various registered Australian pharmacies with a valid prescription. Availability may vary. Chemist2U's partner pharmacy network dispenses Mounjaro with home delivery options where supply is available.

Do I need a prescription for Mounjaro?

Yes. Mounjaro (tirzepatide) is a Schedule 4 (S4) prescription-only medicine in Australia. It requires a valid prescription from a registered medical practitioner following a clinical assessment.

What is the difference between Mounjaro and Ozempic?

Ozempic (semaglutide) is a GLP-1 receptor agonist — it activates one receptor type. Mounjaro (tirzepatide) is a dual GIP/GLP-1 receptor agonist — it activates two receptor types. This is a pharmacological difference in mechanism of action. See our guide: Ozempic and Mounjaro: Understanding the Difference.

What are the side effects of Mounjaro?

Common side effects reported in clinical trials include nausea, diarrhoea, vomiting, and constipation — typically most pronounced during dose escalation. Refer to the TGA-approved Consumer Medicine Information for Mounjaro for a complete list, available from your dispensing pharmacist.
Related: Weight Loss Program · Ozempic in Australia · Ozempic and Mounjaro: Understanding the Difference · Wegovy Australia

Dr Matthew Cullen

MBBS · Founder & CEO, Chemist2U

Dr Matthew Cullen is the founder and CEO of Chemist2U and a medical doctor (MBBS). This page has been reviewed for clinical accuracy and compliance with TGA therapeutic goods advertising requirements. Last reviewed May 2026.

Important Information

The information on this page is provided for general informational purposes only. It does not constitute medical advice and does not advertise or promote the use of any specific prescription medication. Prescription medications can only be accessed after a clinical consultation with an authorised medical practitioner.

All prescriptions are issued at the discretion of the consulting clinician in accordance with Australian medical guidelines. All dispensing is carried out by AHPRA-registered pharmacists. Individual eligibility is determined by the treating clinician.

If you are experiencing a medical emergency, call 000. For health concerns, consult your GP or healthcare provider.

Last reviewed: May 2026 · Compliance: TGA Therapeutic Goods Advertising Code

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